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相关概念视频

Blood Supply to the Digestive System01:16

Blood Supply to the Digestive System

958
Splanchnic circulation refers to the network of blood vessels that supply and drain blood from the abdominal organs involved in digestion, including the stomach, liver, pancreas, intestines, and spleen. This circulation delivers essential nutrients and oxygen while removing waste products from these organs.
Blood Supply to the Digestive System: The splanchnic circulation involves three main arteries: the celiac artery (also known as the celiac trunk) and the superior and inferior mesenteric...
958
Histology of the Gastrointestinal (GI) Tract01:20

Histology of the Gastrointestinal (GI) Tract

734
The GI tract, from beginning to end, is made up of four continuous tissue layers that adjust their structure according to their specific roles. These layers, from innermost to outermost, are known as the mucosa, submucosa, muscularis, and serosa, which are continuous with the mesentery.
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
734
Mucosal Barrier of the Stomach01:25

Mucosal Barrier of the Stomach

530
The gastric glands contain parietal cells that secrete hydrochloric acid (HCl) for digestion. The cells secrete HCl because it is highly corrosive and essential for breaking down food. To achieve this, they secrete hydrogen and chloride ions into the lumen of the gastric glands, which combine to form HCl.
Within parietal cells, carbonic acid is first formed through the reaction of water and carbon dioxide. The dissociation of carbonic acid releases bicarbonate and hydrogen ions. The bicarbonate...
530
Characteristics and Functions of Blood01:26

Characteristics and Functions of Blood

4.2K
Blood is specialized connective tissue comprising about 8% of the body mass. It has a thick, liquid extracellular matrix that contains cells, dissolved proteins, and electrolytes, making it five times more viscous than water. Blood is warm, around 38°C, and has an alkaline pH ranging from 7.35 to 7.45.
The primary function of blood is to transport oxygen and carbon dioxide between tissues and the lungs. Oxygenated blood is bright red, while oxygen-depleted blood is darker. It also carries...
4.2K
Blood Transfusion01:15

Blood Transfusion

518
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
518
The Blood-brain Barrier00:49

The Blood-brain Barrier

46.9K
Overview
46.9K

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相关实验视频

Updated: Jun 9, 2025

Mucin Agarose Gel Electrophoresis: Western Blotting for High-molecular-weight Glycoproteins
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Mucin Agarose Gel Electrophoresis: Western Blotting for High-molecular-weight Glycoproteins

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从血液到粘膜.

Jinyi Tang1,2, Jie Sun1,2

  • 1Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, VA 22908, USA.

Science translational medicine
|October 23, 2024
PubMed
概括

目前的COVID-19疫苗和mRNA助推剂在呼吸道中提供有限的保护. 这表明需要改进的疫苗策略来增强粘膜免疫力,以抵抗呼吸道病毒.

科学领域:

  • 免疫学 免疫学 免疫学
  • 疫苗学 疫苗学 疫苗学
  • 呼吸系统医学 呼吸系统医学

背景情况:

  • 目前的COVID-19疫苗主要针对系统性免疫.
  • 目前关于当前疫苗在诱导强大的呼吸道粘膜免疫力方面的有效性数据有限.
  • 已使用mRNA增强剂来增强对SARS-CoV-2的保护.

研究的目的:

  • 为了评估在当前的COVID-19疫苗接种和mRNA增强后的呼吸道粘膜免疫的诱导.
  • 评估在呼吸道粘膜上疫苗诱导的免疫力是否足够.

主要方法:

  • 关于COVID-19疫苗免疫性当前文献的综述.
  • 对研究粘膜体免疫反应疫苗接种后和增强后的研究进行分析.

主要成果:

  • 目前的COVID-19疫苗诱导了低于最佳的呼吸粘膜免疫力.
  • 即使在使用mRNA增强剂后,呼吸道粘膜的免疫反应仍然不足.
  • 现有的疫苗不能在病毒进入的地方完全建立保护性免疫力.

结论:

  • 目前针对COVID-19的疫苗接种策略需要加强以改善呼吸道粘膜免疫力.

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Using Unfixed, Frozen Tissues to Study Natural Mucin Distribution
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Last Updated: Jun 9, 2025

Mucin Agarose Gel Electrophoresis: Western Blotting for High-molecular-weight Glycoproteins
09:24

Mucin Agarose Gel Electrophoresis: Western Blotting for High-molecular-weight Glycoproteins

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Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E
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Isolation of Lamina Propria Mononuclear Cells from Murine Colon Using Collagenase E

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Using Unfixed, Frozen Tissues to Study Natural Mucin Distribution
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Using Unfixed, Frozen Tissues to Study Natural Mucin Distribution

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  • 需要进一步的研究来开发有效诱导呼吸道保护性免疫力的疫苗.