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相关概念视频

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

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Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
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Introduction to Psychological Disorders01:19

Introduction to Psychological Disorders

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Abnormal behavior, often referred to as mental illness, results from changes in brain function that influence thought patterns, behaviors, and social interactions. Psychologists and psychiatrists typically assess abnormal behavior using three primary criteria: deviance, maladaptation, and personal distress, particularly when these traits persist over long periods.
Deviant Behavior
Deviance in behavior refers to actions or thought patterns that significantly diverge from societal norms or...
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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
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Parkinson's disease arises...
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Biological Causes of Schizophrenia01:29

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Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
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相关实验视频

Updated: Jun 9, 2025

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD
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在ADHD中异常的大脑动力学.

Xiaoyang Xin1, Shuangshuang Gu2, Cuiping Wang3

  • 1Preschool College, Luoyang Normal University, Luoyang 471000, China; Center for Psychological Sciences, Zhejiang University, Hangzhou 310027, China.

Journal of affective disorders
|October 23, 2024
PubMed
概括
此摘要是机器生成的。

动态大脑 (dBEN) 分析揭示了注意力缺陷/多动障碍 (ADHD) 中不同的大脑活动模式. 这些模式与ADHD的严重程度有关,提供了新的诊断见解.

关键词:
注意力缺陷/多动症障碍 注意力缺陷/多动症大脑缩是大脑的缩.动力学 动力学 动力学静止状态功能磁共振成像技术

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科学领域:

  • 神经科学是一个神经科学.
  • 脑部成像 脑部成像
  • 复杂性科学 复杂性科学

背景情况:

  • 大脑 (BEN) 量化大脑活动的复杂性,以前用于ADHD等疾病.
  • 现有的研究往往假定静态的BEN,忽视大脑的动态性质.
  • 在ADHD中BEN的动态仍然在很大程度上未被探索.

研究的目的:

  • 在ADHD中调查动态大脑 (dBEN).
  • 为了比较ADHD患者和健康对照者之间的dBEN模式.
  • 评估 dBEN 动态与ADHD 症状严重程度之间的关联.

主要方法:

  • 使用滑窗方法从静止状态fMRI数据计算dBEN.
  • 分析了98名多动症患者和111名健康对照者的数据.
  • 确定了复发的BEN状态,并检查了它们的分数窗口 (FW) 和平均停留时间 (MDT) 与ADHD状态和症状严重程度相关.

主要成果:

  • 感觉运动和视觉网络中的一个低状态显示ADHD的FW和MDT增加,与症状严重程度呈正相关性.
  • 在默认模式和执行控制网络中的高状态显示ADHD的FW和MDT减少,与症状严重程度负相关.
  • 在ADHD患者和健康对照者之间观察到BEN动态的显著差异.

结论:

  • 研究结果揭示了ADHD中异常的大脑动态,表明大脑网络活动发生了变化.
  • dBEN的变化与ADHD症状严重程度有关,提供了潜在的生物标志物.
  • 这些见解有助于理解ADHD神经病理学,并可能有助于临床诊断.