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Updated: May 16, 2026

Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells
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骨髓瘤瘤发生中的IGFBP5:转移性和非转移性患者中的基因表达特征

G M Guimarães1, F Tesser-Gamba2, A S Petrilli3

  • 1Pediatrics Department, Pediatric Oncology Institute/GRAACC, Federal University of São Paulo, São Paulo, SP, Brazil; Morphology and Genetics Department, Genetics Discipline, Federal University of São Paulo, São Paulo, SP, Brazil.

Gene
|October 23, 2024
PubMed
概括

骨髓瘤 (OS) 患者的IGFBP5基因表达低可能表明非转移性疾病. 对IGFBP5和MAPK基因的进一步研究可以澄清OS中转移的发展.

关键词:
基因表达 基因表达 基因表达在IGFBP5基因.在MAPK的路径.骨质肉瘤骨质肉瘤是什么肺的转移 肺的转移

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Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...