身体活动对动脉样硬化发展的预防性影响:叙述性综述
Yusuke Osawa1,2,3, Yasumichi Arai4,5
1Graduate School of Health Management, Keio University.
Journal of atherosclerosis and thrombosis
|October 23, 2024
概括
定期的体力活动,包括有氧和抵抗训练,通过改善内皮功能和减少炎症,有效地预防动脉样硬化. 个性化炼计划可以优化心血管健康并减轻心脏代谢风险.
科学领域:
- 心血管科学 心血管科学
- 运动生理学 运动生理学
- 预防医学 预防医学
背景情况:
- 动脉样硬化是心血管疾病 (CVD) 死亡的主要原因,由内皮功能障碍,炎症,脂质积累和动脉硬驱动.
- 身体活动是预防动脉样硬化的关键非药物干预措施.
- 了解不同类型的运动对动脉样硬化的影响对于公共卫生至关重要.
研究的目的:
- 审查有氧运动,抵抗运动和联合运动对动脉样硬化发展的预防作用.
- 探索运动改善心血管健康标志物的机制.
- 讨论运动剂量-反应,强度,风险和个性化方法.
主要方法:
- 关于运动和动脉样硬化的里程碑式研究和当前研究成果的综述.
- 分析机制:内皮功能,炎症,脂质状况,动脉硬.
- 讨论运动方式,强度,剂量反应和个性化医学.
主要成果:
- 有氧,抵抗和综合训练表明对动脉样硬化有预防作用.
- 运动可以改善内皮功能,减少全身炎症,增强脂质概况.
- 联合培训提供了协同效益,特别是对于高风险人群.
结论:
- 运动是缓解动脉样硬化和心脏代谢风险的有效策略.
- 个性化的运动处方,可能由可穿戴技术指导,可以最大限度地提高心血管健康效益.
- 对量身定制的运动干预措施进行进一步的研究是有必要的,以实现最佳的心血管疾病预防.
更多相关视频
07:36Induction of Atherosclerotic Plaques Through Activation of Mineralocorticoid Receptors in Apolipoprotein E-deficient Mice
Published on: September 26, 2018
10.0K
05:59Visualization of Intensity Levels to Reduce the Gap Between Self-Reported and Directly Measured Physical Activity
Published on: March 7, 2019
6.7K
相关概念视频
Atherosclerosis III: Management
1
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
1
Atherosclerosis II: Clinical manifestations and prevention
1
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
1
Exercise and Cardiovascular Response
741
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
741
Atherosclerosis I: Introduction
1
Atherosclerosis is a progressive disorder characterized by the buildup of plaques on the arterial inner wall, causing them to narrow and harden over time. These plaques comprise lipids, calcium, blood components, carbohydrates, and fibrous tissue. The process primarily affects the intima of large and medium-sized arteries, reducing blood flow in any artery.Etiology and risk factorsThe cause of atherosclerosis is multifactorial, involving a complex interplay among endothelial injury, lipid...
1
Coronary Artery Disease I: Introduction
3
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
3
Exercise and Cardiac Output
931
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
931
