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Updated: Jun 9, 2025

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells
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Published on: March 28, 2013

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核受体PPARγ的激动剂可以产生偏差信号

Mariah L Rayl1, Michelle D Nemetchek1, Andrew H Voss1

  • 1Biochemistry and Biophysics Graduate Program (M.L.R., T.S.H.), Department of Biomedical and Pharmaceutical Sciences (M.D.N., T.S.H.), and Pharmaceutical Sciences and Drug Design Graduate Program (A.H.V., T.S.H.), University of Montana, Missoula, Montana.

Molecular pharmacology
|October 23, 2024
PubMed
概括

核受体激动剂,包括部分激动剂,通过优先招募协同激活剂,表现出偏向信号. 这种选择性联合激活剂的招募影响了转录结果,为开发向核受体药物提供了洞察力.

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