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Updated: Jun 9, 2025

Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors
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Inhibitory Synapse Formation in a Co-culture Model Incorporating GABAergic Medium Spiny Neurons and HEK293 Cells Stably Expressing GABAA Receptors

Published on: November 14, 2014

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一种与自闭症谱系障碍相关的分子Lingo2的可溶性形式,在神经元中起到激发性突触组织者的作用

Fumiaki Yoshida1, Ryota Nagatomo1, Shun Utsunomiya2

  • 1Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.

Translational psychiatry
|October 23, 2024
PubMed
概括

富含白的重复和免疫球蛋白域含有蛋白2 (Lingo2) 在自闭症谱系障碍 (ASD) 的小鼠模型中被上调. 这种被分泌为sLingo2的蛋白质促进激发性突触的形成,为ASD的发病过程提供了洞察力.

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