这种菌种名为Streptomyces yaizuensis sp. nov. 一种从海绵中分离出来的产生贝尔尼纳米辛C的行为菌种
Miku Takahashi1, Kanata Hoshino2,3, Moriyuki Hamada4
1Department of Biotechnology, Faculty of Life and Environmental Sciences, University of Yamanashi, Kofu, Japan.
The Journal of antibiotics
|October 24, 2024
概括
一种新型的产生抗生素的活性菌种,Streptomyces yaizuensis sp. nov. YSPA8T,是在一个海洋海绵中发现的. 这种通过多相分类学识别的新物种扩大了已知的生产抗生素的微生物的多样性.
科学领域:
- 微生物学 微生物学
- 海洋生物技术 海洋生物技术
- 动氨菌的分类学 动氨菌的分类学
背景情况:
- 海洋环境是各种微生物的庇护所,有可能发现新的生物活性化合物.
- 动菌体,特别是Streptomyces物种,是大量的抗生素生产者.
- 选海洋衍生型菌体对于识别新的抗菌剂至关重要.
研究的目的:
- 为了从分类学上描述一种从海洋海绵中分离出来的新型虫菌株YSPA8T.
- 确定YSPA8T菌株是否代表Streptomyces属内的新物种.
- 调查这种新型菌株在抗生素生产中的潜力.
主要方法:
- 多相分类学分析包括形态学,遗传学 (16S rRNA基因测序,遗传学),基因组学 (ANI,dDDH) 和化学分类学特征.
- 对全细胞水解剂,menaquinones和脂肪酸概况的分析.
- 与密切相关的Streptomyces物种进行比较分析.
主要成果:
- 菌株YSPA8T表现出具有特征的Streptomyces形态与子链.
- 遗传学和基因组分析表明YSPA8与已知的物种不同,Streptomyces clavuligerus ATCC 27064是其最近的亲属.
- 化学分类学数据 (LL-diaminopimelic acid,menaquinones,脂肪酸) 支持将其归类为一种新物种.
结论:
- 菌株YSPA8T代表了Streptomyces属的一个新物种,名为Streptomyces yaizuensis sp. 在新的一年里.
- 这一发现突显了海洋海绵作为新抗生素生产细菌来源的潜力.
- 对Streptomyces yaizuensis产生的伯尼纳米辛C的进一步研究是有必要的.
更多相关视频
09:08From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
Published on: January 13, 2017
17.1K
06:34Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
Published on: July 11, 2016
17.8K
相关概念视频
01:30Bacterial Phylum Actinobacteria
Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
01:30Bacterial Phylum Spirochaetes
Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...
01:29Fungal Group Zygomycota
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
01:26Bacterial Phylum Planctomycetes
Planctomycetes are a group of morphologically distinct bacteria predominantly classified into two orders: Planctomycetales and Brocadiales. These gram-negative bacteria exhibit unique features, including division by budding and the presence of stalks or appendages. Their cells are often found in rosette arrangements, and they are notable for possessing an S-layer in their cell envelope, which is relatively uncommon among bacteria. Additionally, Planctomycetes frequently exhibit intracellular...