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Updated: Jun 9, 2025

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Transgelin 2 保护T细胞脂质代谢和抗瘤功能

Sung-Min Hwang1,2, Deepika Awasthi1,2, Jieun Jeong3

  • 1Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY, USA.

Nature
|October 24, 2024
PubMed
概括

通过调节脂肪酸的摄取,Transgelin-2 (TAGLN2) 对CD8+T细胞代谢和抗癌功能至关重要. 在T细胞中恢复TAGLN2可对抗瘤诱导的压力,增强免疫疗法的有效性.

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