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Updated: Jun 9, 2025

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
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Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Published on: June 14, 2016

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在心力衰竭中,染色体重塑驱动免疫细胞-纤维细胞通信

Michael Alexanian1,2,3, Arun Padmanabhan4,5,6,7, Tomohiro Nishino4,5

  • 1Gladstone Institutes, San Francisco, CA, USA. michael.alexanian@gladstone.ucsf.edu.

Nature
|October 24, 2024
PubMed
概括

研究人员发现,通过向白蛋白-1β (IL-1β),阻断巨细胞中的Brd4可降低心力衰竭和纤维细胞激活. 这揭示了导致心脏病纤维化的关键炎症途径.

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