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Updated: Jun 9, 2025

Using Enzyme-based Biosensors to Measure Tonic and Phasic Glutamate in Alzheimer's Mouse Models
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阿尔茨海默病诱导的神经元携带PSEN1突变,表现出降低了刺激能力

Simon Maksour1, Rocio K Finol-Urdaneta2, Amy J Hulme2

  • 1School of Chemistry and Molecular Bioscience and Molecular Horizons, University of Wollongong, Wollongong, NSW, Australia.

Frontiers in cellular neuroscience
|October 24, 2024
PubMed
概括

在早期阿尔茨海默病 (AD) 中,前列林1 (PSEN1) 突变会降低神经元刺激能力. 这项研究揭示了一种离子通道失衡,导致家族性AD (fAD) 中神经元发射受损.

关键词:
阿尔茨海默氏症是阿尔茨海默氏症的一种疾病.在PSEN1上.在这里,你会发现自己在哪里.对于 iPSCs 来说,这是一个很好的选择.神经元刺激性的神经元刺激性

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