实验室测试在细菌性乳头菌病中的预测意义
Mehmet Çelik1, Yeliz Çiçek2, Ebru Atalay3
1Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, University of Harran, Şanlıurfa, Turkey.
Iranian journal of public health
|October 24, 2024
概括
高水平的费里和低的乙素计数可以帮助预测布鲁塞拉细菌病,当血液培养是负的. 这些实验室发现对于诊断这种常见的动物传播感染至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 兽病是一种普遍存在的动物感染,具有诊断挑战.
- 血液培养,黄金标准,可能会产生错误的阴性.
- 需要布鲁塞洛症中细菌病的预测标志物.
研究的目的:
- 为了确定人口统计学,临床和实验室因素预测细菌病在血病患者.
- 评估各种实验室参数在诊断brucella bacteremia中的重要性.
主要方法:
- 在743名乳病患者 (2012-2022) 进行了回顾性多中心研究.
- 患者分为细菌性和非细菌性组.
- 分析了人口,临床和实验室数据,包括对费里的ROC分析.
主要成果:
- 细菌性患者年轻,发烧,发寒,出汗,恶心,吐和体重减轻更频繁.
- 在细菌群体中观察到较低的白血球,血小板,血红蛋白,MPV,乙酸和中性酸细胞数量.
- 较高的淋巴细胞,ESR,AST,ALT,LDH和费里水平与细菌病有关,费里>67具有很高的预测性.
结论:
- 升高的费里,降低的乙氨基和增加的ESR是布鲁塞拉细菌病的关键指标.
- 这些发现有助于诊断血病细菌病,特别是当培养不确时.
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