身体活动模式与心血管事件和风险因素之间的关联:跨部门和前性研究
Fabrizio Cominetti1, Julien Vaucher1,2, Pedro Marques-Vidal1
1Internal Medicine Division, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
JACC. Advances
|October 24, 2024
概括
身体活动 (PA) 的时间对心血管疾病 (CVD) 风险很重要. 早晨或一整天的运动可能会增加心血管疾病事件的风险,而特定的模式并不总是影响风险因素.
科学领域:
- 心脏病学 心脏病学
- 预防医学 预防医学
- 运动生理学 运动生理学
背景情况:
- 适度强度的体力活动 (PA) 建议获得健康益处.
- 对于预防心血管疾病 (CVD) 的最佳时间仍然存在争议.
研究的目的:
- 评估不同体力活动 (PA) 模式对心血管疾病 (CVD) 风险因素和结果的影响.
- 在基于人口的队列中调查PA时间和心血管疾病风险之间的关系.
主要方法:
- 使用了来自Colaus-PsyCoLaus研究的两个调查 (S1和S2) 的数据.
- 使用手腕穿戴的加速度计和K-means集群进行模式分析来评估PA.
- 包括2,465名 (S1) 和1,692名 (S2) 参与者,平均年龄约为61-64岁.
主要成果:
- 早上PA (7am-12am) 与心血管疾病事件的更高风险相关 (HR:3.33).
- 均分布的每日PA也与心血管疾病事件风险增加有关 (HR: 3.16).
- 在PA模式和高血压,血脂或糖尿病标志物之间没有发现一致的关联.
结论:
- 主要在清晨或在一天中均分布的体力活动可能与心血管事件的更高风险有关.
- 特定的PA时间模式没有显示与关键心血管疾病风险因素 (如高血压或血脂) 的一致关联.
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