在肺癌患者的肺部切除术和细分切除术后,定量计算机断层扫描评估肺功能和补偿
Leqing Chen1,2, Jinrong Yang1,2, Chi Zhang3
1Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Journal of thoracic disease
|October 24, 2024
概括
视频辅助胸部手术 (VATS) 叶片切除和细分切除都会降低癌症后的肺功能手术. 叶切除术显示出更大的补偿能力,而细分切除术的影响最小,有助于个性化手术选择.
科学领域:
- 胸部外科手术 胸部外科手术
- 肺部医学 肺部医学
- 在瘤学瘤学.
背景情况:
- 不同手术技术对肺癌患者术后肺功能的影响尚不清楚.
- 视频辅助胸部手术 (VATS) 叶片切除和细分切除是常见的肺癌手术,对肺功能有不同的影响.
研究的目的:
- 为了比较VATS叶切除术与细分切除术对术后肺功能的影响.
- 为了评估这些程序后肺功能补偿性变化.
- 为了确定影响肺功能下降后手术后的因素.
主要方法:
- 分析了120名接受VATS分管切除 (82) 或分管切除 (38) 的肺癌患者.
- 肺功能,充分透气的肺百分比 (WAL%) 和未经手术的肺 (NOL) 体积在手术前和手术后测量了长达2年的时间.
- 后勤回归确定了与WAL%下降相关的因素.
主要成果:
- 两种VATS分管切除术和分管切除术都降低了肺功能,没有显著的群体间差异.
- 输卵管切除术诱导了ipsilateral NOL体积的更大的补偿性增加.
- 分段切除术导致最小的补偿变化和肺功能影响.
- 肺功能1年下降的预测因子在叶片切除和细分切除组之间有所不同.
结论:
- 这两种手术方法都能降低WAL%,但叶叶切除术显示出更强的肺补偿.
- 定量CT分析对于预测术后肺功能和指导个性化外科决定是有价值的.
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