肥胖与阻塞性睡眠呼吸暂停的发展和严重程度之间的关联:系统性审查
Mohamad Ahmad Alenezi1, Shahd Alabdulathim2, Sultan Abdullah Mutyi Alhejaili3
1Public Health, Maternity and Children Hospital, Ministry of Health, Arar, SAU.
Cureus
|October 24, 2024
概括
肥胖显著增加了阻塞性睡眠呼吸暂停 (OSA) 的风险和严重程度. 控制体重对于预防和治疗肥胖个体的OSA至关重要.
科学领域:
- 医学研究 医学研究
- 公共卫生 公共卫生
- 睡眠医学 睡眠医学
背景情况:
- 全球肥胖流行病与阻塞性睡眠呼吸暂停 (OSA) 发病率上升的同时.
- 肥胖是发展OSA的一个重要风险因素.
- 了解肥胖与OSA的联系对于公共卫生干预至关重要.
研究的目的:
- 系统地评估肥胖与OSA发作和严重程度之间的关联.
- 综合来自多项关于肥胖和OSA关系研究的证据.
- 确定影响肥胖人口OSA的关键因素.
主要方法:
- 在主要的科学数据库 (PubMed,SCOPUS等) 中进行全面的计算机化文献搜索. ) 的情况.
- 包括12项试验,涉及4095名参与者.
- 对数据进行元分析,以确定肥胖指标与OSA严重程度之间的患病率和相关性.
主要成果:
- 在患有OSA的个体中,肥胖的患病率在12.6%至88.9% (总体为31.5%) 之间.
- 身体质量指数 (BMI) 和OSA严重程度 (呼吸暂停-呼吸暂停指数) 之间存在显著的正相关性.
- 肥胖是OSA严重程度的主要决定因素,并发性疾病加剧了管理挑战.
结论:
- 肥胖是阻塞性睡眠呼吸暂停的发展和严重程度的主要因素.
- 体重管理对于预防和治疗OSA至关重要,特别是在肥胖个体中.
- 进一步的研究应该探索年龄,性别和种族对肥胖和OSA关系的影响.
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