在现实生活环境中对STRIDE-II的临床方法:分析和实际建议
Elena Ricart1, Guillermo Bastida2, Daniel Carpio3
1Inflammatory Bowel Disease Unit, Gastroenterology Department, Hospital Clinic Barcelona, IDIBAPS, CIBEREHD, Barcelona 08036, Spain.
在临床实践中实施最新的Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE-II) 准则是具有挑战性的. 障碍包括评估方法和个性化目标,需要实际解决方案,以改善炎症性肠病 (IBD) 患者的治疗结果.
科学领域:
- 胃肠病学 胃肠病学
- 临床实践指南 临床实践指南
- 炎症性肠病 (IBD) 研究研究
背景情况:
- 更新的"在炎症性肠病中选择治疗点" (STRIDE-II) 准则旨在标准化治疗.
- 这些指南的实际应用在临床实践中存在挑战.
研究的目的:
- 评估STRIDE-II建议在日常临床环境中的适用性.
- 确定阻碍实施STRIDE-II.II的障碍.
- 提出可行的策略,以克服这些实施障碍.
主要方法:
- 综合调查,文献评论和专家意见的定性研究.
- 九位IBD专家确定了关键的实施领域:内镜,组织学,超声波,生活质量,生物标志物,症状控制和患者报告的结果 (PRO).
- 在教育课程参与者 (n=55位胃肠科医生) 中进行的调查,随后进行专家讨论和提案生成.
主要成果:
- 报告说,在实现STRIDE-II治疗目标方面存在很大的困难.
- 临床指数和PROs的有限使用 (22%) 用于缓解评估;便calprotectin切断不广泛使用 (70%).
- 需要个性化粘膜治疗目标,并解决像获得成像和专业知识差距这样的障碍.
结论:
- 在临床实践中,STRIDE-II建议面临着重大实施障碍.
- 认真评估和实践措施对于准则的采用至关重要.
- 加强STRIDE-II的采用最终可以改善炎症性肠病 (IBD) 患者的治疗结果.
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