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Updated: Jun 9, 2025

In Vitro Synthesis of Modified mRNA for Induction of Protein Expression in Human Cells
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探索在体外转录mRNA杂质对细胞反应的影响

Julien Camperi1, Brian Roper1, Emily Freund2

  • 1Cell Therapy Engineering and Development, Genentech, 1 DNA Way, South San Francisco, California 94080, United States.

Analytical chemistry
|October 24, 2024
PubMed
概括

制造信使RNA (mRNA) 疗法需要了解杂质. 这项研究将特定的RNA杂质与细胞反应和反应性联系起来,强调用于质量控制的先进分析方法.

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