微生物组和膀癌:益生菌在治疗中的作用
Leila Dadgar-Zankbar1, Maryam Mokhtaryan2, Elnaz Bafandeh3
1Department of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Future microbiology
|October 24, 2024
概括
膀微生物组在健康个体和膀癌患者之间有所不同. 益生菌,尤其是乳酸菌,在预防癌症复发和提高癌症治疗疗效方面显示出潜力.
科学领域:
- 在瘤学瘤学.
- 微生物学 微生物学
- 胃肠病学 胃肠病学
背景情况:
- 膀癌 (BCa) 是一个主要的全球健康问题.
- 膀微生物组在BCa病变发生,进展和治疗中的作用正受到越来越多的关注.
- 了解微生物组和BCa之间的相互作用对于开发新型治疗策略至关重要.
研究的目的:
- 为了研究健康个体和BCa患者之间的膀微生物组合的差异.
- 探索益生菌在预防BCa复发和改善治疗结果方面的潜力.
- 阐明益生菌的抗瘤机制,特别是乳杆菌种类.
主要方法:
- 在健康和BCa人群中对膀微生物组的比较分析.
- 关于益生菌对BCa的影响现有文献的综述.
- 对益生菌疗效的临床前和临床数据的检查.
主要成果:
- 在健康和BCa个体之间,膀微生物组组成存在显著差异.
- 健康的膀通常由链球菌和乳球菌主导.
- BCa患者表现出明显的微生物特征,具体属性因性别而异.
- 益生菌,特别是乳酸菌,通过各种机制表现出抗瘤特性.
结论:
- 膀微生物组在膀癌的发展和进展中发挥着作用.
- 益生菌,特别是乳酸菌,对BCa预防和治疗的增强有前途.
- 对微生物组-BCa轴和益生菌干预措施的进一步研究是有必要的.
相关概念视频
Microorganisms in Medicine and Therapeutics
1
Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
1
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
1
Bacterial Flora of the Large Intestine
392
The gut microbiome is formed by a vast and diverse community of bacteria that colonizes our large intestine. These bacteria start residing in the gut from birth and continue diversifying throughout life, influenced by factors such as diet, lifestyle, and stress. The gut bacterial community also includes bacteria from food and those that enter the colon through the anus.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
392


