早期初潮和高血压在绝经前和绝经后妇女之间的关联: Baependi心脏研究
Liana Carla Albuquerque Peres Martinho1, Divanei Zaniqueli2, Ana Eliza Andreazzi3
1Postgraduate Program in Health Sciences, Federal University of Amazonas (UFAM), Manaus, AM.
Journal of hypertension
|October 24, 2024
概括
早期初潮增加了绝经前妇女高血压的风险. 这种关联在绝经后的妇女中消失了,其中年龄和并发症是关键预测因素.
科学领域:
- 生殖健康 生殖健康
- 心血管健康 心血管健康
- 流行病学 流行病学
背景情况:
- 早期初潮与较高的动脉高血压风险有关.
- 更年期状态对这种关联的影响尚不清楚.
研究的目的:
- 为了检查早期初潮和高血压在绝经前和绝经后妇女之间的关系.
主要方法:
- 对1406名女性 (18-100岁) 的横截面分析.
- 收集的数据:初潮时的年龄,更年期状态,血液动力学,人体测量和生物化学参数.
- 早期初潮定义为<12岁;高血压定义为血压或药物.
主要成果:
- 21.3%的女性经历了早期初潮;38.7%的女性患有高血压.
- 经过初潮早期的绝经前妇女患高血压的几率增加了58% (OR 1.58,CI 1.016-2.461),调整为混因素.
- 在绝经后的女性中,初潮早期并不是预测因素;年龄,肥胖和糖尿病预测高血压.
结论:
- 早期初潮会增加高血压的几率,但仅限于生育年龄的女性.
- 在绝经后的女性中,衰老和糖尿病等并发症可能会掩盖初潮早期对高血压的影响.
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