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在第一个怀孕期的剖腹产和第二次怀孕期的早产之间存在关联
Anders Einum1,2, Quaker E Harmon3, Linn Marie Sørbye2,4
1Department of Clinical Science, University of Bergen, Bergen, Norway.
Acta obstetricia et gynecologica Scandinavica
|October 24, 2024
概括
剖腹产增加了在随后的怀孕中产卵性早产的风险. 这种风险与手术本身有关,而不是自发早产或胎盘疾病.
科学领域:
- 产科和妇科 产科和妇科
- 围产儿医学 围产儿医学
- 生殖健康 生殖健康
背景情况:
- 剖腹产与随后怀孕中早产风险增加有关.
- 这种关联可能源于手术过程或导致剖腹产的潜在情况.
- 了解这种联系对于优化母亲和婴儿的结果至关重要.
研究的目的:
- 调查第一个分娩方式 (剖腹产与阴道) 与第二次怀孕中早产风险之间的关联.
- 为了区分阳产生的风险与自发早产的风险.
- 探索胎盘疾病对这种关联的影响.
主要方法:
- 对挪威298,901名母亲 (1999-2020年) 的数据进行分析.
- 第一次分娩的分类方式:全产,紧急,或计划的剖腹产,或短期的阴道分娩.
- 用于估计第二次怀孕中早产 (<37周) 的相对风险的逻辑双项回归模型.
主要成果:
- 第一次怀孕中剖腹产与第二次怀孕中早产风险增加24%有关 (aRR 1.24).
- 计划剖腹产后 (aRR 1.52) 的风险比紧急剖腹产 (aRR 1.21) 的风险更高.
- 这种增加的风险是特定于iatrogenic早产,而不是自发的早产. 胎盘疾病没有显著改变这种关联.
结论:
- 剖腹产,特别是计划的剖腹产,增加了在随后的怀孕中产卵性早产的风险.
- 这种关联取决于程序,与自发的早产无关.
- 胎盘疾病虽然是早产风险因素,但并不影响先前剖腹产对后来的早产风险的影响.
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