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结合PCNA的活性将RNF168在DNA复制和DNA双链断裂信号中的功能分离

Yang Yang1, Deepika Jayaprakash1,2, Satpal S Jhujh3

  • 1Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, 614 Brinkhous-Bullitt Building, 160 Medical Drive, Chapel Hill, NC 27599, USA.

Nucleic acids research
|October 24, 2024
PubMed
概括

RNF168蛋白在DNA修复和复制中起着双重作用. 研究人员发现了一种新的机制,即RNF168可以独立于其DNA损伤反应功能来支持DNA复制.

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