纳米结构氧化和自然材料的新组合:配方和表征
Anastasia Elsa Prahasti1,2, Tamara Yuanita3, Retno Pudji Rahayu4
1Faculty of Dental Medicine, Airlangga University, Surabaya, Indonesia.
Dental and medical problems
|October 24, 2024
概括
氧化,可可豆提取物和鱼粉作为修复性牙诱导剂的纳米组合的最佳比例是1:1:1. 这种组合显示出优良的材料,抗氧化剂和细胞毒性质,可以刺激牙修复.
科学领域:
- 生物材料科学 生物材料科学
- 牙科再生医学 牙科再生医学
- 在牙科的纳米技术.
背景情况:
- 氧化是一种已知的修复性牙诱导剂.
- 可可豆的皮提取物和鱼粉已经被探索了它们在牙修复方面的潜力,鱼作为源.
- 研究用于增强牙再生的新组合至关重要.
研究的目的:
- 为了确定氧化,可可豆提取物和鱼粉的纳米组合的最佳比例,用于修复性牙诱导.
- 评估这种纳米组合的各种比例的材料,抗氧化剂和细胞毒性质.
- 确定一种促进有效牙再生的配方.
主要方法:
- 制备了不同比例的氧化,可可豆提取物和鱼粉的配方.
- 评估了材料特性,包括粘度,定时间,pH值和可溶性.
- 使用DPPH试验评估抗氧化能力,使用MTT试验评估细胞毒性,对人类牙纸干细胞 (hDPSCs) 进行评估.
主要成果:
- 1:1:1比率显示出最佳的流动性和最短的最终设置时间.
- 这一比率显示了pH值范围为8.5-10.5和有利的溶解率.
- 1:1:1纳米组合显示出显著的激素清除活性,并刺激了hDPSCs的增殖.
结论:
- 纳米氧化物,1:1:1的比例,可可豆提取物和鱼粉是修复性牙诱导的最佳.
- 这种配方具有有利的材料,抗氧化剂和细胞毒性特征.
- 这些发现支持这种纳米组合作为一种新型牙再生剂的潜力.
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