墨西哥西班牙裔患者在患有严重的COVID-19后大约1年,肺功能显著改善
Arturo Cortes-Telles1, Luis Alberto Solís-Díaz1, Heidegger Mateos-Toledo2
1Clínica de Enfermedades Respiratorias, Hospital Regional de Alta Especialidad de la Península de Yucatán, IMSS-Bienestar, Mérida, Mexico.
Experimental physiology
|October 24, 2024
概括
长期的COVID可能会导致长期的肺部问题. 在严重的COVID-19发生一年后,22%的墨西哥西班牙裔患者仍然有肺功能异常,显示出长时间的呼吸影响.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- COVID-19对肺功能的长期影响仍然不清楚,特别是在感染后一年之后.
- 严重的COVID-19可能导致持续的呼吸道并发症,影响患者的康复和生活质量.
研究的目的:
- 研究严重的COVID-19对墨西哥西班牙裔个体肺功能的长期影响.
- 评估恢复时间如何影响严重COVID-19后的肺功能改善.
主要方法:
- 观察性,纵向研究设计.
- 在专门的COVID-19随访诊所评估肺功能和症状.
- 使用z分数和威尔科克森的签名等级测试对随时间变化的统计分析.
主要成果:
- 最初,61%的患者患有肺功能异常,在康复后390天降至22%.
- 68%的患者在最后一次诊所检查时显示肺功能有所改善,30%的患者没有改变.
- 计算机断层扫描 (CT) 扫描显示了33%的患者的地面玻璃不透明;扩散能力与CT纤维化得分相关.
结论:
- 严重的COVID-19幸存者的很大一部分 (22%) 在感染一年后经历了持续的肺功能异常.
- 这项研究表明,即使在康复后,COVID-19也会对肺部健康产生长期影响.
- 根据z分数,没有发现康复时间和肺功能改善之间的显著相关性.
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