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Updated: Jun 9, 2025

Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology
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Identifying PD-1/PD-L1 Inhibitors with Surface Plasmon Resonance Technology

Published on: May 2, 2025

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免疫检查点调节光敏感剂,针对BRD4进行癌症光免疫疗法

Peixia Li1, Yayin Du1, Jingru Qiu1

  • 1Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong Province 250012, P. R. China.

Journal of medicinal chemistry
|October 24, 2024
PubMed
概括

一种针对BRD4的新型光敏感剂BRD-PS通过诱导细胞死亡和降低PD-L1.1的调节,将冷瘤转化为热瘤. 这种方法增强了细胞毒性T淋巴细胞的透,用于有效的癌症光免疫疗法.

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