肺外菌 Mycobacterium abscessus 感染, 法国, 2012-2020 年
Emerging infectious diseases
|October 24, 2024
概括
肺外菌 Mycobacterium abscessus (EP-MAB) 感染通常会在受伤后影响免疫能力强的个体. 超过六个月的治疗方案,可能包括手术,对于这些具有挑战性的感染,显示出有利的结果.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 临床医学 临床医学
背景情况:
- 菌根杆菌的感染很难治疗.
- 肺外M.感染 (EP-MAB) 较肺外形式少见.
- EP-MAB可以影响各种部位,包括骨,关节,皮肤,软组织和淋巴结.
研究的目的:
- 评估肺外M.瘤感染 (EP-MAB) 的治疗方案.
- 分析法国EP-MAB案件的结果.
- 为了确定与EP-MAB相关的患者特征和风险因素.
主要方法:
- 微生物学证实EP-MAB病例的回顾性分析.
- 从2012年至2020年期间在法国诊断的患者收集的数据.
- 包括45名患有各种EP-MAB表现的患者.
主要成果:
- 大多数患者 (62%) 具有免疫能力.
- EP-MAB经常跟随与医疗保健相关的或环境损伤 (27名患者).
- 在80%的患者中,通过中位数为6个月的抗微生物药物治疗方案和55%的手术实现了治愈.
结论:
- 肺外M.瘤感染主要影响受伤后免疫能力较强的患者.
- 良好的结果与长时间的抗微生物药物治疗 (>6个月) 和手术干预有关.
- 定期对患者进行重新评估对于管理EP-MAB至关重要.
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