关联中央和一般的肥胖测量与骨盆器官缩
Keyi Si1, Yingying Yang, Qianqian Liu
1Department of Gynecology and the Clinical Research Unit, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, the Department of Environmental Health, School of Public Health, Shanghai Jiao Tong University School of Medicine, and the Department of Health Management, Naval Medical University, Shanghai, and the Department of Medical Engineering, Peking University Third Hospital, Beijing, China.
中部肥胖症显著增加骨盆器官脱落 (POP) 风险,占病例的20%以上. 没有中心肥胖症的超重个体也面临更高的POP风险.
科学领域:
- 生殖健康 生殖健康
- 肥胖问题研究研究
- 流行病学 流行病学
背景情况:
- 骨盆器官脱落 (POP) 是一种影响女性健康的常见疾病.
- 普遍和中心的肥胖是可疑的POP风险因素.
研究的目的:
- 调查中心和一般肥胖指标与POP发病率之间的关联.
- 量化由于肥胖症而导致的 POP 的人口可归因风险.
主要方法:
- 利用了251,143名参与者 (年龄在39-71岁之间) 的英国生物库数据,这些参与者以前没有POP.
- 员工的腰与身高的比率和体重指数 (BMI) 作为肥胖的衡量标准.
- 应用了考克斯的比例危险模型来估计风险,并计算了可归因于人口的分数.
主要成果:
- 中部肥胖 (腰与身高的比率≥0.5) 与不论BMI的POP风险增加48%有关.
- 中部肥胖占所有POP病例的21.7%.
- 没有中心肥胖的超重 (BMI 25-29.9,腰与身高的比率<0.5) 显示了23%更高的POP风险,导致2.0%的病例.
结论:
- 中部肥胖是发生骨盆器官脱落的重要危险因素.
- 没有中心肥胖症的超重状态也会增加POP风险.
- 这些发现强调了腰与身高的比在评估POP风险时的重要性.
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