尿中的金属与美国儿童和青少年的肥胖有关:一个横截面研究
Xinyun Zhou1, Hongliang Jin1, Yan Zhang1
1School of Public Health, Research Center for Medicine and Social Development, Innovation Center for Social Risk Governance in Health, Research Center for Public Health Security, Chongqing Medical University, Chongqing, China.
Nutrition research (New York, N.Y.)
|October 24, 2024
概括
环境重金属暴露与儿童肥胖有关. 和等某些金属显示出积极的关联,而,和显示出与儿童和青少年肥胖的负面关联.
科学领域:
- 环境健康 环境健康
- 儿童肥胖症 儿童肥胖症
- 毒理学 毒理学 毒理学
背景情况:
- 重金属是广泛存在的环境污染物.
- 暴露于重金属对儿童和青少年健康的担忧越来越大.
- 暴露在重金属和儿童肥胖之间的潜在联系需要调查.
研究的目的:
- 调查个人和混合重金属暴露与儿童和青少年肥胖之间的联系.
- 探索金属暴露对肥胖的潜在性别特异性影响.
主要方法:
- 利用来自国家健康和营养检查调查 (2007-2018) 的数据,对3650名年龄在6-19岁的参与者进行了调查.
- 采用加权的多变量逻辑回归,受限制的立方线,加权的量子和回归,量子g计算回归和贝叶斯核心机器回归.
- 调整了包括年龄,性别,种族,贫困与收入比率和血清胆固醇在内的共变量;根据性别进行了子组分析.
主要成果:
- 肥胖的流行率为21.04%.
- 和与肥胖有积极的关联,而,和则显示出负面的关联.
- 混合金属暴露与肥胖有负相关性 (OR = 0.50).
- 暴露于的情况显示,性别特异性与女性肥胖的负相关性 (OR = 0.83).
结论:
- 重金属暴露与儿童和青少年的肥胖有关.
- 特定金属与肥胖之间的关系可以是正面的或负面的.
- 在金属肥胖症协会中观察到的性别差异凸显了对量身定制的公共卫生战略的需求.
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