代谢性血症在高热性结石形成者中:这是否重要?
Renato V M Starek1,2, Samirah A Gomes1,3, Claudia M B Helou2
1Ambulatório de Nefrolitíase, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Kidney & blood pressure research
|October 24, 2024
概括
代谢性高血症影响4.3%的结石患者在 thiazides,往往与低血和电解质失衡. 监测对于这些高热性腎病患者至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内部医学 内部医学
- 临床化学 临床化学
背景情况:
- 超热性腎病患者的代谢性血病的发生情况尚未得到充分证实.
- 患有高性甲病的患者经常接受 thiazides 治疗,以降低尿路,这可能导致化物损失.
- 在这些患者中常见的酸盐补充剂添加了源.
研究的目的:
- 为了研究在患有高酸性石病的门诊患者中代谢性血病的发生率.
- 在这些患者中识别潜在的风险因素和相关的电解质障碍.
主要方法:
- 对外科患者患有结石的回顾性图表审查 (2013年1月至2021年7月).
- 基于静脉血液气体的代谢性血的诊断:pH≥7.46和碳酸盐>26mEq/L.
- 统计分析以比较有和没有代谢性血症的患者群.
主要成果:
- 在4.3%的患者中诊断出代谢性血症.
- 几乎所有受影响的患者都使用了 thiazide,高血症患者的每日剂量更高.
- 低血症发生在37%的代谢性血症患者中,同时降低了血清化物,和离子水平.
结论:
- 代谢性血是不常见的,但在高性结石形成者的显著.
- 建议对这些患者密切监测低血和其他电解质障碍,特别是那些接受 thiazide 治疗的患者.
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