在民族医学上使用,植物化学和药理学Apocynum venetum L L
Wenli Xie1, Fangjie Li1, Xianrui Ding1
1Research Institute for Marine Traditional Chinese Medicine, The SATCM's Key Unit of Discovering and Developing New Marine TCM Drugs, Key Laboratory of Marine Traditional Chinese Medicine in Shandong Universities, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China; Qingdao Academy of Chinese Medical Sciences Shandong University of Traditional Chinese Medicine, Qingdao Key Laboratory of Research in Marine Traditional Chinese Medicine, Qingdao Key Technology Innovation Center of Marine Traditional Chinese Medicine's Deep Development and Industrialization, Qingdao, 266114, China.
在传统医学中Apocynum venetum L. (Luobuma) 具有丰富的历史,含有371种化学成分,特别是黄类,提供心血管保护和抗炎功效. 本次审查强调了其在管理高血压和心血管疾病方面的潜力.
科学领域:
- 综合医学和植物化学.
- 药理学和人种植物学.
背景情况:
- 百年来,Apocynum venetum L. (Luobuma) 在东亚和东南亚被用于医疗目的.
- 在古代中国文本中记载,并包括在中国药典中,它被认为具有肝脏镇静和镇静等作用.
研究的目的:
- 提供Apocynum venetum L. 叶的传统用途,植物化学物质和药理学机制的全面审查.
- 为了解决缺乏关于这种植物的综合,最新的文献.
主要方法:
- 对1957年至2024年的文章进行系统的文献综述.
- 包括来自Web of Science,PubMed,CNKI,古代文本,论文和论文 (共89个记录) 的数据.
主要成果:
- 在Apocynum venetum L.中确定了371种化学成分,包括黄类,类和多糖类.
- 黄类药物表现出显著的心血管保护,抗癌,抗氧化和抗炎作用.
- 确定了114个非挥发性和257个挥发性成分,生物信息分析表明了进一步的潜在活动.
结论:
- 阿波金 (Apocynum venetum L.) 对高血压有效,对高脂血症,动脉样硬化和心肌损伤有希望.
- 研究结果支持其在预防和管理高血压相关心血管疾病方面的潜力.
- 这份全面的摘要为扩大Apocynum venetum L. 的临床应用提供了科学基础.
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