肺癌和呼吸道瘤的冠状动脉重建:长期结果
Antonio D'Andrilli1, Beatrice Trabalza Marinucci1, Anna Maria Ciccone1
1Department of Thoracic Surgery, Sant'Andrea Hospital, Sapienza University, Rome, Italy.
The Annals of thoracic surgery
|October 24, 2024
概括
对于非小细胞肺癌 (NSCLC) 和呼吸道瘤,手术切除和重建肌是复杂的,但在瘤学上是可靠的. 对于良好的长期结果,建议在可行的情况下使用护细胞节约技术,而不会影响彻底切除.
科学领域:
- 胸部外科手术 胸部外科手术
- 手术瘤学手术瘤学
- 肺部医学 肺部医学
背景情况:
- 针对非小细胞肺癌 (NSCLC) 或呼吸道瘤的肌肉切除是一个具有挑战性的程序.
- 这项研究报告了从一个大体积的中心对切除和重建结果的20年的经验.
研究的目的:
- 评估肺部和呼吸道瘤的瘤结果和瘤切除和重建的安全性.
- 评估接受这些复杂手术的患者的长期存活率和复发率.
主要方法:
- 总共有41名患者接受了针对NSCLC (n=32) 或原发性气道瘤 (n=9) 的骨髓切除.
- 采用了各种手术技术,包括气管袖肺切除术和隔离切除术.
- 在某些特定情况下,使用了辅助程序,如上静脉置换和体外膜氧化.
主要成果:
- 在97.5%的患者中实现了完全切除 (R0).
- 30天死亡率为7.3%,主要并发症率为24.3%.
- 五年总生存率为NSCLC的50.5%,为气道瘤的76.2%;复发率为NSCLC的41.3%,为气道瘤的11.1%.
结论:
- 肺部和呼吸道瘤的冠状动脉重建是一个复杂但在瘤学上健全的程序.
- 适当的患者选择对于实现良好的长期结果至关重要.
- 如果可能的话,应该考虑使用护细胞节约技术来保持肺功能,而不会影响瘤的激进性.
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