对提供给慢性肠衰竭成年人单独复合的家庭亲肠营养处方的描述性分析
Melanie Baker1, Mark Hann1, Simon Lal2
1The University of Manchester, United Kingdom.
Clinical nutrition ESPEN
|October 24, 2024
概括
个人复合的家庭肠道营养 (IC-HPN) 显示了显著的营养剂量变化,一些患者接受的量不足或过多. 这强调了需要在IC-HPN处方中进行更好的标准化,以与临床指南保持一致.
科学领域:
- 临床营养学 临床营养学
- 父母肠道营养是一种营养.
- 营养支持 营养支持
背景情况:
- 家庭肠道营养 (HPN) 需要量身定制的处方,无论是作为单独复合方案 (IC-HPN) 或多室袋 (MCB).
- 关于影响HPN中添加剂类型选择的因素的研究有限.
- 了解IC-HPN中的营养成分和剂量变异对于患者护理至关重要.
研究的目的:
- 为了评估成人IC-HPN处方的营养成分.
- 评估IC-HPN中营养剂量的差异.
- 为了比较IC-HPN营养资料与可用的MCB和国际指南建议.
主要方法:
- 匿名成年IC-HPN处方数据的横截面观察研究.
- 对来自英格兰155名患者处方的245个HPN袋进行分析.
- 数据总结为平均每日数量,考虑到袋子的频率和类型.
主要成果:
- 在IC-HPN中,脂质 (106%), (74%) 和 (67%) 的剂量差异很大.
- IC-HPN袋通常含有比MCB更多的营养物质,除了和酸盐.
- 在IC-HPN和MCB (187.5与49.1 mmol) 之间的摄入量有显著差异.
- 许多患者接受的剂量超出了指导方针的建议 (例如,50%高,67%低,74%低).
结论:
- 在IC-HPN营养剂量中存在显著的变化,可能导致营养缺失或不足.
- 需要进一步的研究来了解影响IC-HPN使用和剂量变化的因素.
- 需要对脂质剂量的临床评估以及对非指导方针一致处方的原因.
相关概念视频
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
83
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
83
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
103
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
103
One-Compartment Open Model for IV Bolus Administration: Estimation of Clearance
62
Clearance is a key pharmacokinetic parameter that quantifies the volume of body fluid from which a drug is entirely removed within a specific time frame. It is crucial in assessing how a drug is eliminated from the body and has critical clinical applications.
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...
In the one-compartment open model for intravenous (IV) bolus administration, clearance is estimated by dividing the elimination rate by the plasma drug concentration. This equation leverages the elimination rate constant and the apparent...
62
Routes of Drug Administration: Parenteral
1.9K
The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
The intravenous route (IV) of drug administration can be further categorized into two types. The bolus injection administers the entire dose rapidly, while an intravenous infusion slowly delivers smaller doses steadily.
The IV route is often...
1.9K
Enteral Nutrition I: Orogastric and Nasogastric Feeding
207
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
207
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
322
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
322


