世卫组织瘤分类第五版的探索性证据地图,用于肺部和胸腺瘤
Christine Giesen1, Javier Del Águila Mejía2,3, Subasri Armon2,4
1Evidence Synthesis Branch, International Agency for Research On Cancer (IARC), World Health Organization, 25 Avenue Tony Garnier, CS 90627, 69366, CEDEX 07, LYON, France. giesenc@iarc.who.int.
Virchows Archiv : an international journal of pathology
|October 24, 2024
概括
这项研究绘制了世卫组织瘤分类第5版中的肺部和胸腺瘤的证据. 大多数研究的证据水平 (LOE) 较低,突出显示需要更高质量的研究来为未来的癌症分类提供信息.
科学领域:
- 病理学 病理学 病理学
- 在瘤学瘤学.
- 基于证据的医学基于证据的医学.
背景情况:
- 世卫组织瘤分类 (WCT) 对癌症诊断和治疗至关重要.
- 病理学的不断进步需要定期更新WCT.
- 在WCT第五版 (WCT-5) 中评估证据水平 (LOE) 对于改进未来版本至关重要.
研究的目的:
- 在WCT-5中创建胸部瘤 (肺部和胸腺) 的证据地图.
- 确定和评估WCT-5胸部瘤卷中引用的研究的证据水平 (LOE).
- 通过突出证据差距,为未来WCT版本的开发提供信息.
主要方法:
- 从WCT-5胸部瘤卷中提取的引用.
- 编码并将引文导入EPPI-Reviewer软件中.
- 使用EPPI-Mapper可视化证据地图,显示瘤类型,描述符和LOE.
主要成果:
- 分析了1434项针对肺部瘤的研究和677项针对胸腺瘤的研究.
- 发现87.7%的肺瘤和80.8%的胸腺瘤参考是低LOE.
- 肺部的侵入性非性腺癌和胸腺状细胞癌得到了最多的引用;肺部的体腺癌和AB型胸腺瘤显示高的LOE.
结论:
- 在WCT-5中,肺和胸腺瘤的证据水平 (LOE) 一般很低.
- 这种证据映射为WCT证据差距地图 (WCT-EVI-MAP) 项目提供了基础.
- 需要更高质量的研究来增强世卫组织瘤分类的未来版本.
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