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Updated: Jun 9, 2025

A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing
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A Protocol for Functional Assessment of Whole-Protein Saturation Mutagenesis Libraries Utilizing High-Throughput Sequencing

Published on: July 3, 2016

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对低丰度单核酸突变的丰富策略

Chen Guo1, Ruolin Ding2, Zhihe Zhao2

  • 1Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu, Sichuan, 610064, China.

Chemistry (Weinheim an der Bergstrasse, Germany)
|October 24, 2024
PubMed
概括

突变丰富方法的进步改善了与疾病相关的罕见遗传变异的检测. 这些技术提高了识别低频突变的灵敏度,这对于基因组学和诊断至关重要,特别是在液体活检中.

关键词:
循环瘤DNA是循环中的瘤DNA.低级别突变检测检测低级别突变检测基因突变丰富的方法单个核酸变体的变体

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