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Updated: Jun 9, 2025

Chromatin Immunoprecipitation Assay for the Identification of Arabidopsis Protein-DNA Interactions In Vivo
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使用表观基因组分析预测Arabidopsis中的蛋白质协同效应

Chih-Hung Hsieh1, Ya-Ting Sabrina Chang1, Ming-Ren Yen1

  • 1Institute of Plant and Microbial Biology, Academia Sinica, Taipei, 115201, Taiwan.

Nature communications
|October 25, 2024
PubMed
概括

QHistone是一个新的数据库,它使用机器学习来预测 histone 修改如何调节 Arabidopsis 中的基因转录. 它有助于研究人员了解蛋白质的作用,并识别共同调节的蛋白质对.

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Although Mendel chose seven unrelated traits in peas to study gene segregation, most traits involve multiple gene interactions that create a spectrum of phenotypes. When the interaction of various genes or alleles at different locations influences a phenotype, this is called epistasis. Epistasis often involves one gene masking or interfering with the expression of another (antagonistic epistasis). Epistasis often occurs when different genes are part of the same biochemical pathway. The...
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