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Updated: Jun 9, 2025

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协作交叉小鼠创始菌株CAST/EiJ作为致命的COVID-19的新型模型的表征

Candice N Baker1, Debra Duso2, Nagarama Kothapalli2

  • 1The Jackson Laboratory, Bar Harbor, ME, USA.

Scientific reports
|October 25, 2024
PubMed
概括

基因多样化的小鼠,包括CAST/EiJ,对SARS-CoV-2关注变种 (VOC) 很敏感,表现出不同的疾病反应. 这些小鼠模型为评估COVID-19治疗方法提供了一个平台.

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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