透明调整器和传统可拆卸设备对混合牙口腔微生物群的影响:一项比较研究
Wanxi Chen1, Jiajun Chen1,2, Ding Bai1
1State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Orthodontics and Pediatric Dentistry, West China Hospital of Stomatology, Sichuan University, No. 14, 3rd Section of Renmin Nan Road, Chengdu, 610041, China.
BMC oral health
|October 25, 2024
概括
透明调整器和传统的可拆卸器件都会通过改变口腔微生物组,增加混合牙儿童的牙损伤风险. 在使用不同的正牙器具时,观察到特定的菌性物种的明显变化.
科学领域:
- 口腔微生物学 口腔微生物学
- 矯正牙科 矯正牙科是一種矯正牙科.
- 儿科牙科 儿科牙科
背景情况:
- 评估与牙矯正器械相关的脏性风险对于维持儿童口腔健康至关重要.
- 传统的可拆卸器械 (RA) 和清晰对齐器 (CA) 是混合牙的常见正牙治疗方法.
- 这些器件对口腔微生物群的影响以及随后的空心致风险需要进一步调查.
研究的目的:
- 为了比较透明对齐器 (CA) 和传统可拆卸设备 (RA) 对混合牙儿童牙风险的影响.
- 分析CA和RA治疗对口腔微生物组组成和多样性的变化.
- 评估与口腔卫生和牙治疗期间下的发展相关的临床参数.
主要方法:
- 一项前性研究,涉及25名接受正牙治疗 (CA或RA) 的儿童.
- 在基线 (T0) 和6个月后期 (T1) 采集膜上方斑块和唾液样本.
- 使用16S rDNA基因测序对口腔微生物组进行分析,并记录DMFT,PI和GI指数.
主要成果:
- 在CA和RA组之间,临床参数 (DMFT,PI,GI) 没有显著差异.
- 在两组中,与T1的斑块相比,唾液中的α多样性增加.
- 在RA组中,β多样性的显著变化和Lactobacillus的增加,在CA组中观察到的趋势. 在物种层面上确定了独特的病原性物种.
结论:
- 透明对齐器和传统的可拆卸器件都会在混合牙科患者的微生物水平上增加 cariogenic 风险.
- ортодонтические设备诱导明显的改变口腔微生物群,特别影响 cariogenic 物种.
- 对口腔微生物群的监测对于在正牙治疗期间控制病风险至关重要.
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