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患有喘的患者的乙氨基酸计数测试因美国医疗保健提供者的类型而异:一项回顾性研究
Sameer Mathur1, Thomas Corbridge2, Elizabeth Packnett3
1University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
概括
在喘患者中,血液中乙氨基酸细胞计数的测试是不理想的,特别是对于那些不经常恶化的人来说. 增加测试,特别是专家的测试,可以帮助确定针对性生物治疗的eosinophilic表型.
科学领域:
- 肺部病理学 肺部病理学
- 过敏和免疫学 过敏和免疫学
- 现实世界的证据研究研究.
背景情况:
- 酸性喘表型可能受益于向治疗.
- 喘患者血液中乙氨基酸细胞计数检测的发生率和频率尚未得到充分确立.
- 了解测试模式对于优化喘管理至关重要.
研究的目的:
- 评估喘患者血液中乙氨基酸细胞计数检测的患病率.
- 根据恶化的频率 (不经常与频繁) 分析测试模式.
- 评估医疗保健提供者类型 (过敏科医生/肺科医生,PCP,其他) 之间的测试差异.
主要方法:
- 使用电子健康记录 (Merative Explorys® Universe) 的回顾性,纵向性,现实世界的研究.
- 包括在2016年1月至2018年12月期间具有≥2个喘诊断码的患者.
- 分析了血液中乙氨基酸细胞计数测试的流行率和频率,按恶化状态和提供者类型分层.
主要成果:
- 与不常见病例相比,患有频繁恶化病例的患者中,血液中乙氨基酸细胞计数检测的发生率更高.
- 过敏学家/肺炎学家子组的检测率明显高于初级保健医生 (PCP).
- 对于频繁的恶化症,订购的平均测试数量更高,特别是在过敏学家/肺病学家组内.
结论:
- 在喘患者中,血中乙氨基酸细胞计数检测的患病率仍然低于最佳.
- 医疗保健提供者应考虑进行常规血液中乙氨基酸细胞计数测试.
- 增加测试可以帮助识别潜在的生物治疗的酸性喘表型.
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