慢性胃炎的组织病理特征及其与Helicobacter pylori感染的关联
Gargi Tignath Shukla1, Sunita Yadav1, Ajay Shukla2
1Hind Institute of Medical Sciences, Barabanki, UP, India.
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
|October 25, 2024
概括
杆菌 (H. pylori) 感染很常见,并与慢性胃炎和胃癌有关. 这项研究发现,在胃活检中,H. pylori与慢性炎症和肠道转化显著相关.
科学领域:
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
- 传染性疾病 传染性疾病
背景情况:
- 杆菌 (H. pylori) 感染影响全球50%的人口,是慢性胃炎 (CG) 的首要原因.
- 长期的H. pylori感染会增加患胃癌的风险.
- 对CG的组织病理学评估对于了解疾病进展至关重要.
研究的目的:
- 用更新的悉尼系统 (USS) 评估慢性胃炎的组织病理变化.
- 为了确定H. pylori感染在消化不良患者中的患病率.
- 调查H. pylori胃炎和其他组织学变量之间的相关性.
主要方法:
- 一项从2017年2月到2018年4月在印度中部进行的前性观察性研究.
- 分析了每个患者的两次腹腔活检:一个用于快速尿解测试,另一个用于组织病理学.
- 所有样品都根据更新的悉尼系统 (USS) 进行了评估.
主要成果:
- 慢性胃炎 (CG) 在83.84%的消化不良患者中被诊断出.
- 在CG患者中,H. pylori的患病率为46.78%.
- 在H. pylori感染,慢性炎症和肠道转化之间观察到显著的关联.
结论:
- 胆囊杆菌感染与胃活检中的慢性炎症和肠道转化症的严重程度密切相关.
- 建议在 antral 活检中发现慢性炎症和肠道转化时提前检测H. pylori.
- 更新的悉尼系统是有效的评估与H. pylori相关的组织病理学变化.
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