根据年龄与肠道准备相关的急性胃病:口服硫酸盐片对抗1L聚乙烯糖醇与甲酸
Jin Young Yoon1, Su Bee Park1, Moon Hyung Lee1
1Department of Internal Medicine, Kyung Hee University Hospital at Gang Dong, College of Medicine, Kyung Hee University, Seoul, Korea.
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
|October 25, 2024
概括
口服硫酸盐片 (OST) 与所有年龄组的1-L聚乙烯甘醇与酸盐 (PEG/Asc) 相比,与急性胃病发病率更高有关. 医生在处方小容量肠道制备剂时应考虑这种风险.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 药理学 药理学是指药理学的学科.
背景情况:
- 越来越多地使用低容量肠道制备剂,如1-L聚乙烯甘醇与酸盐 (PEG/Asc) 和口服硫酸盐片 (OST).
- 这些药物可能会导致急性胃,特别是在老年患者中.
- 在不同年龄组中,急性胃病的比较发病率和PEG/Asc与OST的疗效需要进行研究.
研究的目的:
- 为了比较不同年龄组的1-L PEG/Asc和OST之间的急性胃病发病率.
- 评估这些肠道制备剂的有效性和安全性.
主要方法:
- 这是一项对4711名患者的回顾性研究,这些患者在同一天接受了食道胃管腺镜 (EGD) 和结肠镜检查.
- 患者接受了OST或1-L PEG/Asc.的肠道制剂.
- 收集的数据包括急性胃的EGD发现,波士顿肠道准备量表 (BBPS) 评分,腺瘤检测率 (ADR) 和实验室参数.
主要成果:
- 在所有年龄群体 (年轻人,中年人,老年人) 中,OST组的急性胃病发病率高于1-L PEG/Asc组.
- 在年轻的患者中,与1-L PEG/Asc.相比,OST与显著更高的BBPS和ADR得分相关.
- 在中年或老年人群中,在OST和1-L PEG/Asc之间没有观察到BBPS或ADR的显著差异.
结论:
- 口服硫酸盐片 (OST) 在所有年龄组中与急性胃病的相关性比1-L PEG/Asc更强.
- 医生必须考虑急性胃的风险,使用小容量肠道制备剂,包括OST和PEG/Asc,无论患者的年龄.
相关概念视频
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
53
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
53
Drugs for Treatment of Ulcerative Colitis in IBD
124
Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
124
Drugs Affecting GI Tract Motility: Other Laxatives
172
Laxatives are primarily used to alleviate constipation, a common gastrointestinal disorder characterized by infrequent bowel movements and difficulty passing stools. They work by various mechanisms to increase the volume or frequency of bowel movements. The primary modes of action of laxatives include increasing stool bulk, softening the stool, stimulating intestinal motility, and osmotically drawing water into the intestines.
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
Osmotic or saline laxatives, like magnesium hydroxide or milk of...
172
Peptic Ulcer Disease IV: Management
74
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
74
Endoscopic Procedures I: Esophagogastroduodenoscopy
71
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
71
Prevention of Further Absorption of Poison
785
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
785


