在基于人口的队列中,复发性静脉血栓栓塞的发生率
Tomas Ruthström1, Lovisa Hägg1, Lars Johansson1
1Department of Public Health and Clinical Medicine, Skellefteå Research Unit, Umeå University, Skellefteå, Sweden.
概括
复发性静脉血栓栓塞 (VTE) 的风险因风险因素而异. 癌症患者最初面临的VTE复发率最高,但在五年内,这些比例会相等.
科学领域:
- 心血管医学 心血管医学
- 流行病学 流行病学
- 血液学 血液学 血液学
背景情况:
- 复发性静脉血栓栓塞 (VTE) 的发生率受到时间和风险因素的影响.
- 了解长期复发模式对于患者管理至关重要.
研究的目的:
- 为了确定VTE复发的每年发病率在第一个VTE后的5年内.
- 根据风险因素对复发率进行分层:癌症,其他风险因素,或没有.
主要方法:
- 在瑞典北部的一项队列研究中,确定了1413名第一个VTE (2006-2014) 个体.
- 在5年的随访期内,检查了医疗记录以检查复发的VTE事件.
- 每100人/年的年发病率 (IR) 被计算并按风险组分层.
主要成果:
- 在1413人中,有213人经历了复发性VTE.
- 一年级IR:4.2 (没有风险因素),9.5 (癌症),6.1 (其他风险因素).
- 第五年的IR:4.1 (没有风险因素),5.4 (癌症),2.3 (其他风险因素).
结论:
- 癌症患者在VTE后的最初几年中表现出最高的VTE复发率.
- 在癌症幸存者中,五年后,VTE复发发病率接近没有危险因素的个体.
- 风险分层对于预测和管理VTE复发至关重要.
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