皮肤冠状动脉干预后5年相对生存的性别差异
Jin-Ho Choi1, Jung-Min Choi2, Ki-Hong Choi3
1Department of Emergency Medicine, Samsung Medical Center Seoul, South Korea.
European cardiology
|October 25, 2024
概括
接受皮肤冠状动脉干预 (PCI) 的女性患者的长期存活率低于男性,尤其是老年女性. 这表明,在PCI之后,在这个人口群体中需要改进降低风险的战略.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 生物统计学 生物统计学
背景情况:
- 皮肤冠状动脉干预 (PCI) 的存活率各不相同,性别特异性结果不清楚.
- 相对存活率分析可以通过将PCI患者与一般人群进行比较来解释变异性.
研究的目的:
- 通过皮肤冠状动脉干预 (PCI) 后调查性别特定的生存结果.
- 通过使用相对存活率分析,评估接受PCI的男性和女性之间的长期存活差异.
主要方法:
- 2011年韩国全国PCI队列研究包括48,783名患者.
- 观察和相对存活率在5年内被评估,取决于先前的生存里程碑.
- 根据性别特异性临床特征调整的倾向性得分匹配.
主要成果:
- 未经调整的分析显示,女性的观察和相对存活率较低.
- 在匹配后,女性的观察生存率高,但相对生存率低于男性 (HR 1.19; 95% CI [1.13-1.26]).
- 这一趋势在60岁以上的女性中更为明显,并在随访期间持续存在.
结论:
- 与同龄男性相比,接受PCI的老年女性的5年相对存活率较低.
- 对于PCI后的老年女性,需要加强降低风险的策略.
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