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Updated: Jun 9, 2025

Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation
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Genome-wide Analysis of HDAC Inhibitor-mediated Modulation of microRNAs and mRNAs in B Cells Induced to Undergo Class-switch DNA Recombination and Plasma Cell Differentiation

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通过RNA测序分析探索分散型大B细胞淋巴瘤中的差异表达基因和免疫调节

Nor Adzimah Johdi1, Amanda Seng2, Wei-Kang Lee2

  • 1UKM Medical Molecular Biology Institute, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia.

Iranian journal of medical sciences
|October 25, 2024
PubMed
概括

这项研究确定了扩散性大B细胞淋巴瘤 (DLBCL) 中73个差异表达的基因,揭示了对免疫反应和癌症进展至关重要的下调通路. 这些发现为侵袭性非霍奇金淋巴瘤提供了新的治疗点.

关键词:
扩散大的B细胞淋巴瘤.基因本体学是基因的本体学.豁免权是一种豁免权.有关RNA测序的RNA测序转录组 转录组就是一个转录组.

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相关概念视频

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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