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Updated: Jun 9, 2025

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化学机械调节EZH2局部化控制表皮层-介质细胞过渡

Jessica L Sacco1, Zachary T Vaneman1, Ava Self1

  • 1Department of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802, USA.

Journal of cell science
|October 25, 2024
PubMed
概括

刚性矩阵和TGF-β1信号传递促进EZH2的核局部化 (增强性基因同类物2的增强者),这是基因表达的关键调节者. 这种机制通过EZH2.2将细胞收缩性与纤维化和癌症进展联系在一起.

关键词:
细胞收缩性 细胞收缩性基因组胺基因的修改矩阵的刚度 矩阵的刚度甲基转移酶的使用方法多镇压复杂的复合体转变增长因素的转变

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