生物反对出口功能障碍便秘的疗效:临床结果和有限方法的反应预测因子
Christian Lambiase1,2,3, Massimo Bellini1, William E Whitehead4
1Gastrointestinal Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
生物反疗法对导致慢性便秘的功能性排便障碍有效. 简单的诊断工具,如压力问卷和增强数字直肠检查可以预测生物反的成功,帮助早期的患者转诊.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 盆地地板物理治疗 物理治疗
背景情况:
- 功能性排便障碍 (FDD) 是慢性便秘 (CC) 的主要原因之一.
- 诊断包括门测量 (ARM) 和气球驱逐试验 (BET).
- 生物反 (BF) 是异能排便 (DD) 的标准治疗方法.
研究的目的:
- 评估由于任何FDD导致的CC患者的BF结果.
- 评估用于预测短期BF成功的简单诊断工具.
主要方法:
- 131名耐火性CC患者在BET失败后接受了BF.
- 在BF前的评估包括ARM,紧张问卷和增强数字直肠检查 (DRE).
- BF治疗师对BF前评估结果被蒙蔽了.
主要成果:
- 81名患者 (62%) 对BF有反应.
- 对于DD和不充分的排便推进 (IDP),BF同样有效.
- 具体的问卷答复和DRE发现强烈预测了BF的反应.
结论:
- 由于FDD,BF是CC的主要治疗方法,改善了症状和直肠功能.
- 孤立的骨盆地异常可能对BF没有很好的反应.
- 炼问卷和增强的DRE可以指导BF转诊用于便秘管理.
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