身体炼干预对肺癌幸存者的身体功能参数和血液分析变化的影响:可行性研究
Teresa Soria-Comes1, María Climent-Gregori2, Inmaculada Maestu-Maiques1
1Medical Oncology Department, Hospital Universitario Doctor Peset, 46017 Valencia, Spain.
Clinics and practice
|October 25, 2024
概括
一个为期12周的炼计划改善了非小细胞肺癌 (NSCLC) 幸存者的身体功能和生活质量. 监督计划显示可行性,并提高了患者的福祉.
科学领域:
- 在瘤学瘤学.
- 运动生理学 运动生理学
- 康复医学 康复医学 康复医学
背景情况:
- 肺癌幸存者经常因为持续的全身症状而经历生活质量 (QoL) 的降低.
- 早期非小细胞肺癌 (NSCLC) 手术可能会影响身体表现和整体幸福感.
- 正在探索多组分运动干预措施,以减轻这些治疗后的挑战.
研究的目的:
- 为了评估12周监督的多组分炼计划对早期NSCLC手术患者的体力表现,QoL和代谢标志物的有效性.
- 评估社区为肺癌幸存者提供监督炼计划的可行性和遵守率.
- 为了确定身体功能测试和患者报告的QoL结果的具体改善.
主要方法:
- 参与者接受了为期12周的监督计划,将肌肉力量和有氧训练相结合.
- 使用步行速度,手握强度,30秒坐立 (STS) 测试,6分钟步行测试 (6MWT) 和短物理性能电池 (SPPB) 来评估身体表现.
- 使用EORTC-QLQ-C30问卷,以及各种血液生物标志物来衡量生活质量 (QoL).
主要成果:
- 在6MWT距离,STS重复和SPPB分数 (p <0.01) 中观察到显著改善.
- 患者报告的QOL,包括功能和症状得分,显著改善 (p < 0.05和p < 0.01).
- 代谢标志物显示胆固醇,甘油三和IGF-1显著下降,前专辑蛋白增加 (p <0.05).
结论:
- 对NSCLC幸存者来说,一个为期12周的监督,基于社区的多组分炼计划是可行的,其坚持率为70.35%.
- 该干预显著提高了身体表现,并改善了手术后患者的生活质量.
- 这项运动计划提供了一种可行的策略,以改善肺癌幸存者的康复和福祉.
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