功能大脑网络的层次和模块化组织中的性别差异:从层次和模块化分析的洞察力
Wenyu Chen1, Ling Zhan1, Tao Jia1
1College of Computer and Information Science, Southwest University, Chongqing 400715, China.
Entropy (Basel, Switzerland)
|October 25, 2024
概括
男性和女性表现出不同的大脑网络层次结构. 雌性表现出更高的模块化,而雄性具有更复杂的大脑层次结构,影响认知功能.
科学领域:
- 神经科学是一个神经科学.
- 网络科学 网络科学
- 认知科学 认知科学
背景情况:
- 性别差异观察到的神经机制是日常功能和神经精神疾病的基础.
- 功能性大脑网络的层次组织是理解神经机制的关键.
- 以前的研究还没有完全探索大脑网络层次结构中的基于性别的差异.
研究的目的:
- 研究人类大脑网络层次组织中的性别差异.
- 为了确定大脑网络的复杂性和模块化程度是否在男性和女性之间有所不同.
- 识别与基于性别的层次差异相关的特定网络模式.
主要方法:
- 使用了静止状态功能磁共振成像 (fMRI) 数据.
- 对个体大脑网络的测量层次和最大模块化.
- 采用共同分类矩阵来分析共识级别的层次组织.
主要成果:
- 在层次复杂性和模块化之间发现了显著的负相关性.
- 平均而言,女性的网络模块化程度更高.
- 平均而言,男性表现出更复杂的层次化大脑组织.
- 在背部注意网络 (DAN) 和视觉网络 (VIN) 中,在性别之间观察到不同的区域相互作用模式.
结论:
- 男人和女人的大脑利用不同的网络拓来实现认知功能.
- 层次结构和模块化之间的反向关系凸显了大脑网络组织中的平衡.
- 研究结果提供了关于性别特异性大脑功能和神经精神疾病潜在影响的见解.
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