通过灰色质量评估语言侧面化卷:大脑瘤手术中术前规划的含义
Daniel Solomons1,2, Maria Rodriguez-Fernandez1,2, Francisco Mery-Muñoz3
1Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Santiago 7820436, Chile.
Brain sciences
|October 25, 2024
概括
灰质体积 (GMV) 分析补充了功能性MRI (fMRI) 用于大脑语言映射. 在健康个体和脑瘤患者中,GMV预测了语言横向化,在复杂的病例中提高了准确性.
科学领域:
- 神经成像是一种神经成像.
- 神经科学是一个神经科学.
- 放射学 放射学是一门学科.
背景情况:
- 功能性MRI (fMRI) 是语言横向化的标准,但在脑瘤患者中面临挑战.
- 认知障碍,神经可塑性和人造物质可以限制fMRI的准确性.
- 灰色物质体积 (GMV) 分析提供了一个稳定的,使用基于声素的形态学 (VBM) 的补充方法.
研究的目的:
- 为了研究GMV和fMRI衍生的语言横向化之间的关系.
- 评估GMV分析对健康个体和左半球脑瘤患者的有用性.
- 为了提高术前语言映射的准确性.
主要方法:
- 分析了22名健康参与者和28名脑瘤患者的MRI数据.
- 在语言任务中使用fMRI评估语言侧面化.
- 使用VBM测量语言区域的GMV,并分析了与横向化相关的关联.
主要成果:
- 健康的参与者:左半球的优势与左上方的GMOV相关.
- 瘤患者:与右半球GMV增加相关的非典型横向化.
- GMV准确地预测了fMRI语言侧面化 (AUCs 78.3%94.2%).
结论:
- 在语言区域的GMV分析是对fMRI进行语言主导性评估的有价值的辅助.
- 这种方法显示了术前语言映射的潜力,特别是当fMRI受到损害时.
- 建议对更大的队列进行进一步研究,以确认临床效用.
更多相关视频
09:16Study Design for Navigated Repetitive Transcranial Magnetic Stimulation for Speech Cortical Mapping
Published on: March 24, 2023
1.4K
10:15Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia
Published on: July 2, 2013
17.8K
相关概念视频
Lateralization
311
Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.
311
Cerebral Hemispheres
301
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
301
Higher Mental Functions of the Brain: Language
764
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
764
