在意大利中部一所大学兽医医院的猫身上使用抗菌剂:一项回顾性研究
Matilde Vernaccini1, Lucia De Marchi1, Angela Briganti1
1Veterinary Teaching Hospital, Department of Veterinary Sciences, University of Pisa, 56124 Pisa, Italy.
Antibiotics (Basel, Switzerland)
|October 25, 2024
概括
猫的抗菌素处方在各医院单位之间有所不同,仅限于使用敏感性测试. 改进检测是打击抗微生物药物耐药性和支持"一个健康"原则的关键.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 监测抗微生物药物使用对于有效管理和打击耐药性至关重要.
- 了解处方模式有助于制定优化抗微生物药物有效性的策略.
- 抗菌素耐药性对动物和人类健康构成重大威胁.
研究的目的:
- 分析和比较兽医教学医院内科和重症监护病房的抗菌素处方实践.
- 确定最常被处方的抗微生物药物及其使用途径.
- 评估对抗微生物药物处方的诊断基础和敏感性测试支持.
主要方法:
- 从2021-2022年对1164只非手术猫的抗菌素处方进行了回顾性分析.
- 从医院的管理软件 (OCIROE) 中提取的数据.
- 对药物选择,施用途径,治疗条件和诊断支持进行分析的处方.
主要成果:
- 阿莫西西林 - 克拉夫兰酸和安皮西林分别是内科和重症监护中最常被处方的抗微生物药物.
- 25%的处方抗微生物药物是最高优先级的关键重要或B类.
- 尿道,胃肠道,呼吸道和全身系统是最常见的治疗;只有11%的处方得到了敏感性测试的支持.
结论:
- 存在显著的机会来加强抗微生物药物管理,特别是通过增加敏感性测试.
- 通过更多地依赖诊断数据,可以改进针对性的抗微生物治疗.
- 该研究强调了一种健康方法在解决兽医环境中抗菌素耐药性的重要性.
更多相关视频
08:33Quantitative Polymerase Chain Reaction-based Analyses of Murine Intestinal Microbiota After Oral Antibiotic Treatment
Published on: November 17, 2018
12.9K
09:59Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
Published on: July 21, 2023
1.2K
相关概念视频
Antibiotic Selection
Overview
Antimicrobial Effectiveness
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
Automated Microbial Diagnostics
Automated diagnostic analyzers have transformed clinical microbiology by providing rapid and reliable methods for pathogen identification and antibiotic susceptibility testing. Among these systems, the Vitek 2 is widely used because it automates the traditionally labor-intensive processes of microbial identification (ID) and antibiotic susceptibility testing (AST), delivering standardized and timely results that are essential for effective patient care.Microbial Identification with ID CardsThe...
Clinical Significance of Antibiotic Resistance
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
