树精油基纳米乳液的抗菌和细胞毒性潜力 用于口水的应用
Dione Glauco Batista1, William Gustavo Sganzerla2, Lysa Ribeiro da Silva1
1Multi-User Laboratory, Graduate Program in Environment and Health, Planalto Catarinense University, Lages 88509-900, SC, Brazil.
Antibiotics (Basel, Switzerland)
|October 25, 2024
概括
树精油纳米乳液显示了对Streptococcus mutans的抗菌活性. 这种创新的牙科材料为预防性牙科和改善口腔健康提供了潜力.
科学领域:
- 在牙科的纳米技术.
- 自然产品化学 自然产品化学
- 微生物学 微生物学
背景情况:
- 牙损是一个重要的全球健康问题,通常是由Streptococcus mutans引起的.
- 传统的治疗方法可能有局限性,这推动了对新型抗菌剂的研究.
- 树精油以其潜在的生物活性而闻名.
研究的目的:
- 开发和描述一种树精油纳米乳液.
- 为了评估抗菌素对Streptococcus mutans的有效性.
- 评估细胞毒性和在口腔卫生产品中的潜在应用.
主要方法:
- 使用Eucalyptus citriodora和Eucalyptus globulus精油合成纳米乳液.
- 物理化学特征 (粒子大小,多分散性指数,泽塔潜力,pH,形态).
- 子表面粘膜细胞的体外抗菌试验和细胞毒性测试.
主要成果:
- 纳米乳液表现出最佳的物理化学特性 (约. 100纳米大小,PDI~0.3,泽塔电位19~30mV,pH~7,球形).
- 已经证明了对Streptococcus mutans的显著抗菌活性.
- 功能化口水配方显示出细菌静止和杀菌作用,细胞活力>50%.
结论:
- 树精油纳米乳液具有适合牙科应用的特性.
- 开发的纳米乳液显示出作为预防性牙科创新的药物具有前途.
- 这种方法可以有助于保持口腔和全身健康.
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