临床药剂师驱动的周末抗菌药物管理覆盖在四级医院的影响
Hazem Elrefaei1,2, Wasim S El Nekidy1,2, Rama Nasef1
1Department of Pharmacy Services, Cleveland Clinic Abu Dhabi, Abu Dhabi P.O. Box 112412, United Arab Emirates.
Antibiotics (Basel, Switzerland)
|October 25, 2024
概括
在周末与受过传染病培训的药剂师一起实施抗菌药物管理服务,显著增加了干预措施,并减少了住院时间. 这一倡议促进了合理的抗生素使用,并优化了患者护理计划.
科学领域:
- 药房实践 在药房实践.
- 传染性疾病 传染性疾病
- 抗微生物药物管理委员会
背景情况:
- 一项新的倡议将药房抗微生物管理 (AMS) 服务扩展到周末.
- 该研究评估了一个受过传染病 (ID) 培训的临床药剂师在周末AMS的影响.
研究的目的:
- 为了评估药剂师驱动的周末AMS计划的影响.
- 评估对AMS干预措施,抗生素使用和患者结果的影响.
主要方法:
- 回顾性,单中心,前后准实验性研究.
- 2020年 (实施前) 和2021年 (实施后) 从电子医疗记录 (EMR) 收集的数据.
- 主要结局:AMS干预次数;次要结局:抗生素治疗日 (DOT),住院时间 (LOS),与医疗相关的Clostridioides difficile感染 (CDI) 和与感染相关的再入院.
主要成果:
- 实施后记录的干预措施显著增加 (451对115),主要针对WHO观察抗生素.
- 住院时间 (LOS) 的中位数显著下降 (16天对27.5天).
- 平均抗生素治疗日 (DOT) 增加 (8 vs. 7),但CDI或再入院率没有显著变化.
结论:
- 药剂师主导的周末AMS服务增加了干预措施,并优化了患者护理.
- 该倡议证明了对抗微生物药物的明智使用,并有助于减少医院LOS.
- 建议在更大的前性研究中进一步复制.
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