肺动脉损伤后内心心左心室尾闭塞:已知的和未知的
Aashish Katapadi1, Jalaj Garg2, Aditya Mansabdar1
1Kansas City Heart Rhythm Institute, Overland Park, Kansas, USA.
JACC. Clinical electrophysiology
|October 25, 2024
概括
肺动脉损伤 (PAI) 是左心房附带关闭 (LAAC) 的罕见并发症. 这次审查发现,PAI经常与心脏吸管发生并具有高死亡率,因此需要低怀疑门.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 医疗器械并发症 医疗器械并发症
背景情况:
- 左心房尾关闭 (LAAC) 是一种常见的中风预防替代方案,用于口服抗凝药的禁忌患者.
- 肺动脉损伤 (PAI) 是内心LAAC后的一个罕见但严重的并发症,现有的文献有限.
研究的目的:
- 系统地审查已发表的报告和FDA MAUDE数据库,以查找LAAC后的PAI病例.
- 了解与PAI相关的证据,机制,患者特征,结果和风险因素.
主要方法:
- 进行了系统的文献审查和对FDA MAUDE数据库的分析.
- 对已确定的PAI病例进行了审查,以了解患者的人口统计,程序细节,临床表现,管理和结果.
- 还审查了避免PAI的策略.
主要成果:
- 确定了36例PAI病例 (16例来自文学,20例来自MAUDE).
- 双密封装置 (75%) 和叶片闭塞装置 (19.4%) 常见的PAI,呈现为心脏吸管 (61.1%) 或在24小时内停止 (19.4%) (50%) 或更晚 (38.9%).
- 治疗包括手术 (52.8%) 或心周切割 (16.7%),死亡率高达33.3%.
结论:
- 在LAAC之后的PAI可以立即表现或延迟,强调需要低怀疑门.
- 在LAAC之后,血液动力学上显著的快速心周溢出应促使考虑PAI.
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